Multiple mononeuropathy in eosinophilic granulomatosis with polyangiitis – a case report
DOI:
https://doi.org/10.67667/NEU.v25i1.163Keywords:
Churg-Strauss syndrome, multiple mononeuropathy, vascular neuropathy, еosinophiliaAbstract
Eosinophilic granulomatosis with polyangiitis (EGPA), formerly known as Churg-Strauss syndrome, is a systemic disease characterised by asthma, pulmonary infiltrates, hypereosinophilia, and systemic vasculitis. Vasculitic neuropathy in EGPA commonly is presented as multiple mononeuropathy but rarely as polyradiculopathy.
Central nervous system manifestations are uncommon compared to peripheral nervous system involvement. We present a 49-year-old patient in which EGPA was diagnosed based on the presence of asthma, nasal polyps, chronic pansinusitis, peripheral blood eosinophilia, positive antineutrophil cytoplasm antibodies and simultaneous involvement of the peripheral and central nervous systems.
Early identification and treatment of the patients are essential, since early immunosuppressive therapy is often successful.
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