Нарушения на съня при пациенти с миастения гравис
Ключови думи:
https://doi.org/10.67667/NEU.v25i1.157Ключови думи:
Миастения гравис, нарушения на съня, сънна апнея, безсъние, двигателни нарушенияАбстракт
Миастения гравис (МГ) е автоимунно заболяване, което се дължи на наличието на антитела срещу ацетилхолиновите рецептори (AChR), мускулно-специфичната тирозин киназа (MuSK) и други свързани протеини в постсинаптичната мембрана. Основни изяви на заболяването са патологичната мускулна уморяемост на напречно-набраздената мускулатура и мускулната слабост поради нарушено предаване на нервния импулс. Много от пациентите с МГ страдат от различни нарушения на съня. При невромускулните заболявания, включително и МГ, най-често срещани са дихателните нарушения като сънна апнея, безсънието и двигателните нарушения по време на сън. Те могат да утежнят основното заболяване и да влошат количеството и качеството на съня, което ги прави и социално значими. Важно е те да бъдат навременно диагностицирани и лекувани.
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